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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
16.97
Human Site:
Y556
Identified Species:
23.33
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
Y556
V
H
P
K
D
T
R
Y
Q
H
L
K
G
K
N
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
Y556
V
H
P
K
D
T
R
Y
Q
H
L
K
G
K
N
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
P460
F
R
G
L
Q
N
H
P
M
V
L
P
I
C
S
Dog
Lupus familis
XP_538837
1256
139671
Y556
V
H
P
K
D
P
R
Y
Q
H
L
K
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
Y555
V
H
P
K
D
P
R
Y
Q
H
L
K
G
K
C
Rat
Rattus norvegicus
Q04462
1264
140350
Y556
V
H
P
K
D
P
R
Y
Q
H
L
K
G
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
V382
G
I
A
T
Q
V
V
V
E
K
K
L
W
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
H537
P
Q
D
Q
R
Y
K
H
L
K
G
H
H
V
V
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
Q492
Q
A
X
K
D
R
G
Q
F
K
E
V
K
D
N
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
H505
P
S
D
S
R
Y
Q
H
L
K
G
K
T
V
L
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
L446
L
N
L
Y
R
E
T
L
N
N
P
M
V
V
P
Honey Bee
Apis mellifera
XP_395202
1043
121057
E440
I
A
K
N
L
F
I
E
I
K
E
N
P
M
V
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
R447
M
V
V
P
T
C
S
R
S
K
D
V
I
E
P
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
K505
Q
A
V
I
Q
A
L
K
D
R
G
L
Y
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
M491
R
G
A
K
N
N
E
M
R
L
G
L
C
S
R
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
E492
K
V
I
E
Q
L
K
E
K
N
L
Y
V
G
Q
Red Bread Mold
Neurospora crassa
P28350
1093
123334
P488
G
L
F
V
K
K
E
P
N
P
M
K
I
P
L
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
80
N.A.
86.6
86.6
N.A.
0
N.A.
0
20
6.6
0
0
0
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
93.3
N.A.
13.3
N.A.
20
20
20
20
6.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
18
12
0
0
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
6
6
6
% C
% Asp:
0
0
12
0
36
0
0
0
6
0
6
0
0
6
0
% D
% Glu:
0
0
0
6
0
6
12
12
6
0
12
0
0
6
6
% E
% Phe:
6
0
6
0
0
6
0
0
6
0
0
0
0
0
0
% F
% Gly:
12
6
6
0
0
0
6
0
0
0
24
0
30
6
0
% G
% His:
0
30
0
0
0
0
6
12
0
30
0
6
6
0
0
% H
% Ile:
6
6
6
6
0
0
6
0
6
0
0
0
18
0
0
% I
% Lys:
6
0
6
42
6
6
12
6
6
36
6
42
6
24
0
% K
% Leu:
6
6
6
6
6
6
6
6
12
6
42
18
0
0
12
% L
% Met:
6
0
0
0
0
0
0
6
6
0
6
6
0
6
0
% M
% Asn:
0
6
0
6
6
12
0
0
12
12
0
6
0
0
18
% N
% Pro:
12
0
30
6
0
18
0
12
0
6
6
6
6
6
12
% P
% Gln:
12
6
0
6
24
0
6
6
30
0
0
0
0
0
6
% Q
% Arg:
6
6
0
0
18
6
30
6
6
6
0
0
0
18
12
% R
% Ser:
0
6
0
6
0
0
6
0
6
0
0
0
0
6
18
% S
% Thr:
0
0
0
6
6
12
6
0
0
0
0
0
6
0
0
% T
% Val:
30
12
12
6
0
6
6
6
0
6
0
12
12
18
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% W
% Tyr:
0
0
0
6
0
12
0
30
0
0
0
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _